Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p276 | (1) | WCRB2014

Glucocorticoids trigger macrophage migration inhibitory factor (MIF) secretion by decidualized human endometrial stromal cells in vitro: the modulatory effect of Bisphenol A

Mannelli Chiara , Szostek Anna , Ciaffarafa Sara , Carotenuto Claudiopietro , Ietta Francesca , Romagnoli Roberta , Piotrowska-Tomala Katarzyna , Paulesu Luana , Skarzynski Dariusz

Introduction: Pro-inflammatory cytokines are important mediators of the early phases of gestation. Among all these cytokines, the macrophage migration inhibitory factor (MIF) plays significant roles in pregnancy establishment. In many cell types, low concentrations of glucocorticoids (GCs) are known to enhance MIF secretion, but the effect of GCs on endometrial cells has not been elucidated. Bisphenol A (BPA) is an environmental chemical that can alter reproductive physiology ...